Uncovering QC-Friendly Methods for Accurately Separating Multivalent LNPs to Advance Next Generation Drug Products Towards Approval
Time: 9:00 am
day: Conference Day Two
Details:
- Identifying robust methods to disrupt lipid nanoparticles (LNPs) to access and analyze encapsulated nucleic acid payloads. Applying platform analytical technologies to accelerate the transition from development to clinical application
- Highlighting challenges encountered during the testing of multivalent LNP formulations, particularly those containing varying ratios of multiple payloads
- Leveraging QC-friendly, HPLC-based methods to differentiate and quantify closely sized nucleic acid payloads within multivalent LNPs, ensuring suitability for regulated environments
NEW DATA