Uncovering QC-Friendly Methods for Accurate Quantification of mRNAs in Multivalent LNPs to Accelerate Product Development

Time: 9:00 am
day: Conference Day Two

Details:

• Identify robust methods to disrupt LNPs for accessing and analyzing encapsulated mRNA payloads. Highlight challenges in testing multivalent LNPs, especially those with varying payload ratios
• Leverage QC-friendly, HPLC-based methods to differentiate and quantify closely sized NA payloads within multivalent LNPs, ensuring suitability for regulated environments
• Apply platform analytical technologies to accelerate transition from development to clinic

Speakers:

Kala Dasuri Kala Dasuri is the Analytical CMC Leader at Sanofi’s mRNA Center of Excellence, where she brings over a decade of experience in analytical method development Read more