Using SAXS for Optimal LNP Development
Time: 1:00 pm
day: Conference Day One
Details:
- SAXS provides detailed information about the size, shape and internal structure of LNPs. SAXS can also detect the presence of mRNA within LNPs (as shown by the correlation peak at q = 1nm⁻¹)
- By comparing SAXS data of different LNP formulations, researchers can optimize the nanoparticle structure for better mRNA protection and cellular uptake
- Structural information gained by SAXS helps researchers understand how different LNP formulations affect mRNA encapsulation and potential delivery efficiency
