Predictive In Vitro Profiling of LNP-Induced Innate Immune Response Using an iPSC-Derived Model

Time: 2:00 pm
day: Conference Day Two

Details:

• An unlimited, standardized source that shrinks the bench-to-bedside gap: Enabling high-throughput in-vitro screens of LNP inflammatory responses, speeding translational development

• Deliver stronger, more reproducible cytokine readouts than primary cells: Clearer signals reveal formulation–response relationships that traditional assays miss

• Mirror in-vivo cytokine signatures: allowing precise rank-ordering of LNPs innate immune response

Speakers:

Baixue (Dorothy) Xiao Baixue (Dorothy) Xiao, Ph.D., is a LNP-drug-delivery researcher at Genentech. She designs and optimizes LNPs, builds high-throughput in-vitro screens, and validates LNP formulations in vivo. Read more