Kala Dasuri
Seminars
Thursday 20th November 2025
Uncovering QC-Friendly Methods for Accurate Quantification of mRNAs in Multivalent LNPs to Accelerate Product Development
9:00 am
- Identify robust methods to disrupt LNPs for accessing and analyzing encapsulated mRNA payloads. Highlight challenges in testing multivalent LNPs, especially those with varying payload ratios
- Leverage QC-friendly, HPLC-based methods to differentiate and quantify closely sized NA payloads within multivalent LNPs, ensuring suitability for regulated environments
- Apply platform analytical technologies to accelerate transition from development to clinic
