Kala Dasuri

Company: Sanofi

Job title: CMC

Bio:

Kala Dasuri is the Analytical CMC Leader at Sanofi’s mRNA Center of Excellence, where she brings over a decade of experience in analytical method development and validation. Her work focuses on identifying and implementing robust analytical control strategies to support the development of mRNA-based vaccines and therapeutics. Before transitioning to industry, Kala conducted postdoctoral research at Tufts University, where she investigated the mechanistic pathways of protein degradation in aging and age-related diseases. She is also an active contributor to industry-wide collaboration as an expert member of BioPhorum’s Gene Therapy workstreams.

Seminars:

Uncovering QC-Friendly Methods for Accurate Quantification of mRNAs in Multivalent LNPs to Accelerate Product Development 9:00 am

Identify robust methods to disrupt LNPs for accessing and analyzing encapsulated mRNA payloads. Highlight challenges in testing multivalent LNPs, especially those with varying payload ratios Leverage QC-friendly, HPLC-based methods to differentiate and quantify closely sized NA payloads within multivalent LNPs, ensuring suitability for regulated environments Apply platform analytical technologies to accelerate transition from development to…Read more

day: Conference Day Two