Baixue (Dorothy) Xiao

Company: Genentech

Job title: Postdoctoral Fellow

Bio:

Baixue (Dorothy) Xiao, Ph.D., is a LNP-drug-delivery researcher at Genentech. She designs and optimizes LNPs, builds high-throughput in-vitro screens, and validates LNP formulations in vivo. During over nine years research experience on NP drug delivery, Dorothy has engineered various NP platforms for diverse modalities, such as mRNA, siRNA, and small-molecule; mapped how NP physicochemical traits and protein corona drive immune activation and function; led NP-mediated immunomodulation studies for tissue regeneration; and created ligand-decorated NPs for cell-specific delivery. Her work spans pharmaceutical science, biochemical cellular pharmacology, immunology, and translational medicine and is grounded in cross-functional communication, strategic collaboration, and project leadership with chemistry, biology, and data-science teams.

Seminars:

Predictive In Vitro Profiling of LNP-Induced Innate Immune Response Using an iPSC-Derived Model 1:00 pm

An unlimited, standardized source that shrinks the bench-to-bedside gap: Enabling high-throughput in-vitro screens of LNP inflammatory responses, speeding translational development Deliver stronger, more reproducible cytokine readouts than primary cells: Clearer signals reveal formulation–response relationships that traditional assays miss Mirror in-vivo cytokine signatures: allowing precise rank-ordering of LNPs innate immune response NEW DATARead more

day: Conference Day Two